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Newcastle Disease

By: Office International des Epizooties, Paris

Classification of the Causative Agent – Virus family Paramyxoviridae, genus Rubulavirus

Temperature:    Inactivated by 56°C/3 hours,60°C/30 min
pH:                   Inactivated by acid pH
Chemicals:        Ether sensitive
Disinfectants:    Inactivated by formalin & phenol
Survival:           Survives for long periods in feces     

Epidemiology

Hosts

            ·  Many species of birds, domestic & wild
            ·  Morality /morbidity rates vary among species & strains
            ·  Chickens most susceptible poultry, ducks/geese least
            ·  Carrier state may exist in psittacine & some wild birds

Transmission

            ·  Direct contact with secretions, feces, from infected birds
            ·  Contaminated feed, water, implements, premises, clothes

Sources of Virus

·  Respiratory discharges, feces
            ·  All parts of the carcass
            ·  Virus shed during incubation & convalescence
            ·  Psittacines can shed virus intermittently for over 1 year

Diagnosis –

Incubation is four to six days

Clinical Diagnosis

·  Respiratory and/or nervous signs:
       *  gasping & coughing
       *  drooping wings, dragging legs, twisting of the head    &  neck, circling, depression, loss of appetite, paralysis
·  Partial or complete cessation of egg production
·  Abnormal eggs, watery albumen
·  Greenish watery diarrhea 
·  Swelling around eyes & neck
·  Morbidity/mortality depend on strain, vaccine immunity, environmental conditions & flock health

Prevention & Control –

No treatment

Medical Prophylaxis

·  Vaccination with live and/or oil emulsion vaccine
            ·  Live B1 & La Sota strains administered in drinking water
            ·  Other infections may aggravate vaccine reaction

Sanitary Prophylaxis

·  Strict isolation of outbreaks
·  Destruction of all infected & exposed birds
·  Thorough cleaning and disinfection of premises
·  Proper carcass disposal (bury or burn)
·  Respiratory discharges, feces
·  All parts of the carcass
·  Pest control in flocks
·  Depopulation followed by 21 days before restocking
·  Avoid contact with birds of unknown health status
·  Control of human traffic
·  1 age group per farm breeding recommended

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